Ovasitol for PCOS – Why it’s my number 1 supplement

Updated April 2022

Recently I’ve been struggling. I had abdominal surgery in February and my PCOS has worsened as a result. I’m doing everything I know how to get things under control. And that is why I am so glad that I came across Ovasitol for PCOS. It has made such a huge difference for me and as you (hopefully) know, I love sharing the things that really work for women with PCOS.

So, let me tell you a little more about Ovasitol.

What is Ovasitol?

Ovasitol is a supplement designed for women with PCOS. It is a combination of D-Chiro and Myo-inositol in a 40:1 ratio.

Let’s break that down a little. If you’ve been following PCOS Diet Support for a while, you may know that Myo-inositol has always been my number 1 PCOS supplement. It has helped me conceive, lose weight, manage my cravings and generally stay in control of my PCOS. So, why am I now recommending Ovasitol?

To answer that question properly, I need to explain a little more about Myo- Insoitol and D chiro inositol.

Click here to order Ovasitol at the best price



I’ve written about Myo-inositol before (you can see that article here) so I won’t go into all of that detail again. But to briefly summarise it here:

  • Myo-inositol is one of 9 other kinds of Inositols.
  • It is the most common inositol occurring in the body.
  • It plays a role in the insulin signaling pathway
  • It is really important in helping insulin enter cells effectively by working on the insulin receptor of the cell.
  • It also plays a role in way in which insulin works on the cell and it makes insulin’s role more effective.

Remember that women with PCOS have irregularities in the way the body responds to glucose and insulin so if you work on the insulin pathway, you are likely to see some improvements in PCOS symptoms.

What improvements can you hope to see with and inositol supplement, I hear you ask?

Myo-inositol supplementation has been shown to:

  • lower testosterone levels
  • helps to restore normal ovarian function and induces spontaneous ovulation
  • helps to restore regular menstrual cycles
  • improves insulin sensitivity
  • promote egg quality
  • helps to improve insulin resistance

So, how does D-chiro Inositol compare to Myo-Inositol?

D-Chiro Inositol

D-chiro inositol (DCI) is formed from myo-inositol. It is not present in as high a concentration as myo-inositol. Now, women with PCOS are thought to have a deficiency of DCI. You see, DCI is formed from myo-inositol but women with PCOS struggle to make that conversion. We also lose more DCI in our urine than we should. (1)

Now, researchers suggest that this deficiency and impaired use of DCI may result in or at least contribute to insulin resistance in women with PCOS.

But, what does DCI actually do? How does it help women with PCOS?

Well, DCI helps to improve the efficacy of insulin. In doing this, it also improves: (2)

  • blood pressure and cholesterol levels
  • serum levels of androgens (testosterone)
  • ovulatory function and helps to restore normal menstrual cycles

That sounds pretty good to me.

Why combine the two?

For the last 4 years I have been taking myo-inositol on it’s own and it has worked well for me. So, why change? Why is combined myo-inositol and DCI better than myo-inositol on it’s own?

Well, myo-inositol is really important for improving egg quality and ovarian function. This is obviously particularly important if you are trying to conceive. And DCI has been shown to address the insulin resistance to commonly seen in PCOS (in fact, research suggests that most obese women with PCOS and 50% of lean women with PCOS have insulin resistance) (3)

Using a combined approach helps to tackle PCOS from a systemic level, as well as at the level of the ovary (4)

Also, some recent research showed that taking the combined therapy of myo-inositol and d chiro inositol together had a better improvement on the metabolic factors of women with polycystic ovary syndrome than just d chiro inositol on it’s own (5).

Where can I get Ovasitol?

ovasitol pcosYou can order Ovasitol through a US based company, Theralogix. It is the only company that offers the combined MI and DCI and most importantly, it’s in the right ratio. You see, too much DCI has been shown to impair egg development so getting the dosage and ratio right is important.

Click here to order Ovasitol at the best price

When you order the Ovasitol, you’ll get a 3 month supply made up of easy to use sachets. Just mix one sachet in water twice a day. It’s really easy and less messy than the big tub of Inositol I used to use.

Some commonly asked questions about Ovasitol

Can I take Ovasitol while taking the birth control pill?

Remember, ovasitol works to improve ovarian functions as well as on the metabolic aspects of PCOS. So, whilst you may not be ready to start a family, ovasitol can help with other symptoms of PCOS.

So, taking inositol while on birth control can help to improve insulin levels and insulin sensitivity which could promote normal hormone profiles on women with PCOS.

Can I take Ovasitol and Letrozole at the same time?

Letrozole is often prescribed for women who are struggling to conceive . It can help to improve ovulation rates.

There is no evidence to suggest that inositol would interfere with letrozole and vice versa. In fact, they may work well together as Letrozole improves ovulation and inositol has been shown to improve egg quality.

Of course, it’s always best to speak with your physician before taking any new supplements.

Ovasitol pills or powder form?

I am often asked about taking inositol pills or if the powder form is better. Ovasitol is actually not available in capsules or pill form. It is only available as a powder that is mixed with water on a daily basis.

How does Ovasitol help when I am trying to conceive?

Taking Ovasitol on a daily basis improves hormone imbalance and helps to improve ovarian response. This means that you are more likely to ovulate each month and have a more frequent and regular menstrual cycle.

Ovasitol also helps to improve egg quality. This is because it reduces oxidative stress on the eggs (6)

So, if you are trying to conceive, taking Ovasitol can help you to get pregnant by improving your chances of ovulation and by improving egg quality.

How long does it take Ovasitol to work for PCOS?

Many of the women that I work with report seeing improvements in a couple of weeks, from some weight loss to improved skin and reduced acne.

But, for best results, Ovasitol should be taken continuously for at least 3 months. This is because it can take a few months for your hormones to balance.

Can I take Ovasitol while pregnant?

Ovasitol is a water soluble vitamin and is not stored in the body. This means that it is safe to take during pregnancy.

There is actually some research showing that taking inositol during pregnancy can help to prevent gestational diabetes (7)

So, if you are struggling with PCOS and want to get pregnant, Ovasitol is a safe supplement to take.

If you are unsure at all, make sure that you talk to your healthcare provider before starting Ovasitol.

What is the difference between Inopholic Alpha and Ovasitol?

Inopholic Alpha is also an inositol supplement but it only contains myo-inositol, not the combination of myo and d-chiro inositol.

Also, Inopholic Alpha contains folic acid and Alpha-lactalbumin. The Alpha-lactalbumin is said to increase the absorption of inositol.

Do I need a prescription for Ovasitol?

Nope, you don’t need a prescription for inositol. You can order it online here.

Does Ovasitol have side effects?

There can be some very mild side effects when taking Ovasitol but it is generally very well tolerated. If anything, you may experience mild stomach upset.

Can I take Ovasitol with Metformin?

Metformin is an insulin sensitising drug and helps to improve insulin sensitivity. It is often prescribed for women with PCOS. Although Ovasitol is generally safe to take alongside Metformin, it is best to check with your healthcare provider as the combination of the two may lower blood sugar levels too much.

What is the typical recommended dose of Ovasitol?

Ovasitol is normally taken in the morning and evening. One sachet contains 2g on myo-inositol, which is the typical recommended dose.

Final Verdict

Right at the beginning, I told you that my PCOS was not where I want it to be at the moment, since my surgery in February. I’ve gained 3kg in 2 months and my cycle which is normally pretty regular has gone MIA.

I only received my Ovasitol a week ago and have been taking it for 6 days. In that time I have lost 1kg (I’ve also been much stricter with my eating). Still no period but I know that may take a bit of time.

With these benefits in such a small amount of time, as well as all of the research that I have read and shared, I definitely think Ovasitol is my new number 1 PCOS supplement.
I highly recommend it and think you’ll see great improvements in your PCOS.

So, if you’re rearing to go and give it a try, you can order some here, for the best price.

Click here to order Ovasitol at the best price

If you already take Ovasitol, please leave me a comment below and let me know what improvements you’ve seen since taking it! I’d love to hear from you!

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Tarryn Poulton

Tarryn Poulton

Tarryn Poulton is a PN1 Certified Nutrition Coach and PCOS expert who has been a leader in the online PCOS space for over 8 years. Tarryn has the support of leading clinicians from around the world who support her scientific approach to understanding and talking about PCOS this includes all medical journals and ongoing research. You can read more about Tarryn and the team here.

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